As one who is now interviewing applicants for my firm, I can say that I have never cared whether I received a handwritten, typed, or email thank-you, or if I even received one at all. Nor have I ever been on a recruiting conference call and heard anyone comment on the medium of thank-you or even the presence of thank-you. I can also say that I have seen two applicants lose the job for making a typo or saying something stupid in the thank you, so beware.