Do you happen to know the cross streets? I'm thinking the 300 block of N. West is in the area of Penn St., but I could be wrong. If so, as Kilroy said, that's not a great area, but you really don't have much to worry about. Carlisle has a pretty low crime rate. The Penn St. area is a lower income area and there has been some drug activity there, but I don't really think it's unsafe. I would just judge by how comfortable you feel when you go look at the place.