1. Spybot SD 1.3 : http://www.safer-networking.org/en/mirrors/index.htmlMake sure you update all the signatures with the live update feature...With SpyBot, make sure you use the "Immunize" feature, and enable the 2 resident protections available from within the advanced mode...this will help to alert you when something has been modified without your knowledge (and consent).2. CWShredder : http://www.majorgeeks.com/download3019.htmlThese 2 apps, with AdAware, are a pretty good defense against spyware infections...3. Delete all Windows and Internet Explorer Temp files as well.4. You may have to boot into Safe mode and then run the apps in order to clean some of the crud out.5. If these steps don't help, you pretty much have to use RegMon to determine what's accessing which system resources, and when.(http://www.sysinternals.com/ntw2k/source/regmon.shtml)Good luck!